Lifendra: The First Once-Daily Oral PCSK9 Inhibitor

There’s something new when it comes to cholesterol treatment: Lifendra.

Hi everyone, I’m Dr. Raymond Singer.

There has been an exciting new development in cardiovascular medicine. The FDA has approved Lifendra, also known as anlisotide, the first once-daily oral PCSK9 inhibitor for lowering LDL cholesterol, often called “bad” cholesterol.

How Effective Is Lifendra?

Clinical trials showed that Lifendra lowered LDL cholesterol by nearly 60% when added to existing cholesterol-lowering therapies. That’s an impressive reduction and is comparable to injectable PCSK9 inhibitors.

Who May Benefit?

Lifendra is intended for adults with high cholesterol, including those with inherited forms of high cholesterol, particularly patients who have not reached their LDL goals despite healthy lifestyle changes and statin therapy.

The Bottom Line

As a cardiac surgeon, I always remind my patients that lowering cholesterol is only one part of protecting your heart.

  • Don’t smoke
  • Exercise regularly
  • Eat a heart-healthy diet
  • Control blood pressure
  • Manage diabetes
  • Take medications consistently

Lifendra represents an exciting new option for patients who need additional LDL lowering and prefer taking a pill instead of injections. It is another step forward in preventing heart disease and helping people live longer, healthier lives.

I’m Dr. Raymond Singer. I hope this was helpful. Stay informed, take care of your heart, and I’ll see you next time.

Dr. Raymond Singer explains Lifendra, the first FDA-approved once-daily oral PCSK9 inhibitor, a new treatment option for lowering LDL cholesterol and improving cardiovascular health.

Interested in my book? You can buy it on Amazon!

(𝘛𝘩𝘦 𝘷𝘪𝘦𝘸𝘴 𝘦𝘹𝘱𝘳𝘦𝘴𝘴𝘦𝘥 𝘪𝘯 𝘮𝘺 𝘱𝘰𝘴𝘵𝘴 𝘢𝘳𝘦 𝘮𝘺 𝘰𝘸𝘯 𝘢𝘯𝘥 𝘥𝘰 𝘯𝘰𝘵 𝘳𝘦𝘱𝘳𝘦𝘴𝘦𝘯𝘵 𝘵𝘩𝘦 𝘷𝘪𝘦𝘸𝘴 𝘰𝘧 𝘮𝘺 𝘦𝘮𝘱𝘭𝘰𝘺𝘦𝘳 𝘰𝘳 𝘢𝘯𝘺 𝘰𝘳𝘨𝘢𝘯𝘪𝘻𝘢𝘵𝘪𝘰𝘯.)

Recent Posts

Look Beyond the Smile: How Are You Really Doing?

Look Beyond the Smile: How Are You Really Doing?

Sometimes the person struggling the most is not the person you would expect. They may still go to work, care for their family, answer their texts, and even make you laugh. Dr. Raymond L. Singer asks us to look beyond the smile, ask how someone is really doing, and stay long enough to hear the answer.

read more
Thank You to the Night Shift

Thank You to the Night Shift

While most of the world is settling in for the evening, the hospital night shift is just beginning its workday. Dr. Raymond Singer reflects on the dedicated people who keep hospitals running around the clock and care for patients during some of the most vulnerable hours of their lives.

read more
Celebrating a Remarkable Career of Caring

Celebrating a Remarkable Career of Caring

Dr. Raymond Singer celebrates his dear colleague and friend Marie Baker Mo, whose remarkable career has been defined by compassion, leadership, mentorship, and an unwavering commitment to caring for patients and those who care for them.

read more

Featured

Pages

Questions? Comments?
Reach out to me here:

14 + 7 =

About The Author

Dr. Raymond Singer

Dr. Singer has been in practice since 1992 and has, to date, performed over 8,456 surgeries. His practice interests include complex valve, coronary and aneurysm surgery, as well as prevention and treatment of lung cancer.

 

2023 Top Doc

2023 Top Doc

 

TikTok