Lifendra: The First Once-Daily Oral PCSK9 Inhibitor

There’s something new when it comes to cholesterol treatment: Lifendra.

Hi everyone, I’m Dr. Raymond Singer.

There has been an exciting new development in cardiovascular medicine. The FDA has approved Lifendra, also known as anlisotide, the first once-daily oral PCSK9 inhibitor for lowering LDL cholesterol, often called “bad” cholesterol.

How Effective Is Lifendra?

Clinical trials showed that Lifendra lowered LDL cholesterol by nearly 60% when added to existing cholesterol-lowering therapies. That’s an impressive reduction and is comparable to injectable PCSK9 inhibitors.

Who May Benefit?

Lifendra is intended for adults with high cholesterol, including those with inherited forms of high cholesterol, particularly patients who have not reached their LDL goals despite healthy lifestyle changes and statin therapy.

The Bottom Line

As a cardiac surgeon, I always remind my patients that lowering cholesterol is only one part of protecting your heart.

  • Don’t smoke
  • Exercise regularly
  • Eat a heart-healthy diet
  • Control blood pressure
  • Manage diabetes
  • Take medications consistently

Lifendra represents an exciting new option for patients who need additional LDL lowering and prefer taking a pill instead of injections. It is another step forward in preventing heart disease and helping people live longer, healthier lives.

I’m Dr. Raymond Singer. I hope this was helpful. Stay informed, take care of your heart, and I’ll see you next time.

Dr. Raymond Singer explains Lifendra, the first FDA-approved once-daily oral PCSK9 inhibitor, a new treatment option for lowering LDL cholesterol and improving cardiovascular health.

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(𝘛𝘩𝘦 𝘷𝘪𝘦𝘸𝘴 𝘦𝘹𝘱𝘳𝘦𝘴𝘴𝘦𝘥 𝘪𝘯 𝘮𝘺 𝘱𝘰𝘴𝘵𝘴 𝘢𝘳𝘦 𝘮𝘺 𝘰𝘸𝘯 𝘢𝘯𝘥 𝘥𝘰 𝘯𝘰𝘵 𝘳𝘦𝘱𝘳𝘦𝘴𝘦𝘯𝘵 𝘵𝘩𝘦 𝘷𝘪𝘦𝘸𝘴 𝘰𝘧 𝘮𝘺 𝘦𝘮𝘱𝘭𝘰𝘺𝘦𝘳 𝘰𝘳 𝘢𝘯𝘺 𝘰𝘳𝘨𝘢𝘯𝘪𝘻𝘢𝘵𝘪𝘰𝘯.)

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Dr. Raymond Singer

Dr. Singer has been in practice since 1992 and has, to date, performed over 8,456 surgeries. His practice interests include complex valve, coronary and aneurysm surgery, as well as prevention and treatment of lung cancer.

 

2023 Top Doc

2023 Top Doc

 

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